Published April 2025

Colorectal Cancer (CRC) is the third most common cancer in the United States and the second leading cause of cancer death. Epidemiologic studies have shown an increasing incidence of CRC in people aged 45 to 54 in the past decade. Therefore, the US Preventive Services Task Force (USPSTF) has recommended a change in the screening age for adults and lowered it from 50 to 45 years. The Colorectal Cancer Alliance reports that young-onset colorectal cancer may be the deadliest cancer by 2030 in people 20-49 years old, and data shows that delays in diagnosis occur in 15-50% of young-onset cases.

Colorectal cancer is one of the few cancers that is preventable, and screening for CRC is the best way individuals can prevent it. A study published in the World Journal of Gastroenterology notes that despite the various CRC screening modalities offered, U.S. screening rates remain around 60%. Screening rates are particularly poor among underserved populations, including low-income, African American, and Hispanic populations. The lowest use of screening for CRC was reported by people without a usual source of health care and uninsured individuals.

Reasons for delaying screening vary and can include fear of the procedure, fear of the outcome, lack of understanding of the various tests available, cultural barriers, and language barriers. Health care providers have a responsibility to educate patients on the screenings they need, provide them with options, and address any barriers that may affect compliance.

While a colonoscopy is considered the gold standard for CRC screening, some individuals prefer alternative tests. MVP continues to offer at-home testing for CRC in 2025.

Sources:

• Overcoming Patient-Reported Barriers to Colorectal Cancer Screening
• Young-Onset CRC Facts | Colorectal Cancer Alliance
• The revised colorectal cancer screening guideline and screening burden at community health centers | Scientific Reports